About AMNPR
The Alternative Medicine & Natural Product Research Lab is a part of the Centre for Research Excellence (CRE) which is one of the lead laboratory for scientific research on the diverse medicinal plants and natural products that are not generally considered part of conventional medicine. This organisation is working to mitigate the urgency of new and reliable source of therapeutic agents and knowing their scientific proof. This lab is working in a holistic approach through Biochemistry, Molecular Biology and Simulation methods to find out the alternative medication system for mainly emerging non-communicable diseases.
About Principle Investigator
Professor Dr. Md Atiar Rahman is the current chairman of the Department of Biochemistry and Molecular Biology at the University of Chittagong. He graduated in the discipline of Biochemistry and molecular biology from the University of Dhaka. He completed his Ph.D. from Japan and postdoc from Durban, SA. He is the principal investigator of the Laboratory of Alternative Medicine and Natural product research. Besides providing services to a lot of organizations, he is the joint secretary of Bangladesh society for biochemistry and molecular biology (BSBMB). He always tries to expand ample scopes in the field of research. He has a lot of publications in many top quality journals in his field from different publishing groups. He has the power of producing cogent inspirations that help the students to give their best approaches in research. He is one of the most sedulous researchers in Bangladesh. In his way of life, he is a comprehensive, hedonist, altruist and optimistic person.
Dr. Md. Atiar Rahman
Professor
Department of Biochemistry and Molecular Biology
University of Chittagong, Chittagong-4331, Bangladesh
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NYAR webinar on Functional Foods for Immuno-Boosting
19/05/2020 @ 11:30 am - 1:30 pm - বিজ্ঞানীদের জন্য যে বয়সটি সাধারণতঃ সবচেয়ে সৃষ্টিশীল ও ফলপ্রদ সেই বয়সের তরুণ বিজ্ঞানীদের প্রতিভা অন্বেষণ ও বিকাশের লক্ষ্যকে সামনে রেখে একবিংশ শতাব্দীর শুরুতে বিশ্বের বিভিন্ন দেশে “ইয়ং একাডেমি (YA)” যাত্রা শুরু করে। এরই ধারাবাহিকতায় বাংলাদেশের তরুণ বিজ্ঞানীদের কণ্ঠস্বরের প্রতিনিধিত্ব করতে দেশের শীর্ষস্থানীয়...
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Some of Our Research Highlights (Recent)
Pharmacological effect of methanolic and hydro-alcoholic extract of Coconut endocarp
Cocos nucifera used as natural remedies in a wide variety of diseases. The current experiment aimed to determine the qualitative phytochemicals, anxiolytic, anti-diarrheal, antiinflammatory, thrombolytic and cytotoxic actions of C. nucifera endocarp, which extracted by using methanol (MeOH-CNE) and the hydro-alcohol (HaE-CNE).
Intervention in Neuropsychiatric Disorders by Suppressing Inflammatory and Oxidative Stress Signal and Exploration of In Silico Studies for Potential Lead Compounds from Holigarna caustica (Dennst.) Oken leaves
Holigarna caustica (Dennst.), a popular plant used in folk medicine in Bangladesh, is often used by the local folk practitioner to treat a variety of chronic diseases. The present research is an attempt to find out an innovative therapeutic prospect for the management of neuropsychiatric disorders. The methanol extract of H. caustica leaves (MEHC) were utilized on various behavioral tests for assessing anxiolytic, anti-depressant, and anti-inflammatory activities.
Xanthones protects lead-induced chronic kidney disease (CKD) via activating Nrf-2 and modulating NF-kB, MAPK pathway
Xanthones from a tropical fruit of Garcinia mangostana L. is known to possess a wide spectrum of pharmacologic properties, including antioxidant, anti-bacterial, anti-inflammatory, and antidiabetic activities. The current study aimed to assess the possible protective effects of xanthones against lead acetate (PbAc)-induced chronic kidney disease (CKD).
Leea macrophylla (Roxb.) root extract reverses CCl4 induced liver injury through upregulation of antioxidative gene expression: a molecular interaction for therapeutic inception
This study investigated the restorative effect of Leea macrophylla ethanol root extract (LMERE) in carbon tetrachloride (CCl4) induced hepatic injury. It also tried to unfold the underlying mechanism through ligand-receptor interactions. Prior to conduct the CCl4 induced animal model study, the in vitro antioxidative capacities of LMERE were investigated.
Padina tenuis (marine alga) attenuates oxidative stress and streptozotocin-induced type 2 diabetic indices in Wistar albino rats
Marine algae are ecologically important in the food chain and some of have demonstrated wide range of pharmacological properties including antidiabetic activities. This research was aimed to investigate the diabetes healing effect of a phytochemically active marine alga Padina tenuis.
Relevance of electrolytes, creatinine and uric acid in progression of type 2 diabetes mellitus in Bangladeshi population
This research aimed to analyze the association of serum uric acid, creatinine, and electrolytes as potential risk factors for developing type 2 diabetes mellitus in Bangladeshi population.
In vivo and in vitro pharmacological activities of Tacca integrifolia rhizome and investigation of possible lead compounds against breast cancer through in silico approaches
The study was conducted to evaluate the analgesic, anti-inflammatory, antipyretic properties of ethanolic extract of Tacca integrifolia rhizome (EETI) in mice and cytotoxic effects in brine shrimp nauplii followed by a PASS prediction study for some isolated compounds of T. integrifolia.
Antinociceptive and Anxiolytic and Sedative Effects of Methanol Extract of Anisomeles indica: An Experimental Assessment in Mice and Computer Aided Models
Anisomeles indica (L.) kuntze is widely used in folk medicine against various disorders including allergy, sores, inflammation, and fever. This research investigated the antinociceptive, anxiolytic and sedative effects of A. indica methanol extract.
Antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of organic and aqueous extracts of Hopea odorata leaves and in silico PASS prediction of its isolated compounds
Hopea Odorata, locally known as Telsur (Bangladesh), has some traditional uses as folk medicine. This study aims to investigate the antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of H. odorata leaf extracts as new therapeutic prospects predicting the activity of some of the isolated compounds of this plant.
Leea macrophylla Roxb. leaf extract potentially helps normalize islet of β-cells damaged in STZ-induced albino rats
This research aims to investigate the protective effects Leea macrophylla Roxb polyphenols on streptozotocin‐induced diabetic rats. Polyphenolic assays were undertaken through established methods.
Our Ongoing Achievements
Lab Resources
A focus on pharmacological screening and understanding the mechanisms at the molecular level has placed renewed importance on laboratory and research spaces. We have designed and collaborated with other labs in such orient that help us to investigate the research question thoroughly and producing data in a flawless manner. Besides, we are working on adding new and latest lab resources that will fuel us to ensure a quality research environment.
It’s no surprise that exceptional research requires cutting-edge tools and laboratories. Our faculty, researchers, graduate students, and undergrads take advantage of our state-of-the-art facilities to fuel their innovative — and often unprecedented — explorations.
Our featured lab resources
For sample preparation and identification
- Rotary evaporator
- Soxhlet apparatus glass
- Incubator
- Centrifuge Machine
- Capillary Electrophoresis Instrument
- LC-MS Instrument
- HPLC machine
- Gel Image Capture System
- Gel Electrophoresis Instrument
For Molecular level
- Nucleic Acid Purification Instruments
- DNA Thermal Cycler
- PCR Workstation
- Real Time PCR machine
- Flow Cytometer
Miscellaneous
- Analytical Balances
- Cryogenic Refrigerator
- Laboratory Vacuum Pumps
- Autoclave Sterilizer
- Hot Plate With Magnetic Stirrer
- UV-Vis Spectrophotometer
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Our Academic and Research Collaboration
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Working hours
Sunday - Thursday : 9:00-17:00 Hrs
(Phone until 15:30 Hrs)
Friday - 8:00-14:00
We are here
Department of Biochemistry and Molecular Biology
University of Chittagong, Bangladesh
Phone:88-031-726311 (11-14) ext 4334
Fax:+88-031-2606014
Email: atiar@cu.ac.bd
Alternative Medicine & Natural Product Research (AMNPR)
Department of Biochemistry and Molecular Biology
University of Chittagong, Bangladesh